Venous air embolism related to the use of a pressure device for rapid blood transfusion

Abstract

AbstractA 70 year old woman received a transfusion of packed red blood cells via the distal port of a subclavian central venous catheter. In order to facilitate flow, the blood pack was placed within a manually inflatable pressure bag. When the patient's oxygen saturation and systolic blood pressure fell precipitously, it was noticed that the blood pack was empty and that air was present along the entire length of the intravenous tubing. A provisional diagnosis of venous air embolism was made. Management consisted of positioning the woman head‐down in the left lateral decubitus position and ventilating with 100% oxygen. Air was unable to be aspirated from the affected central venous catheter port. Her condition improved and her subsequent intensive care unit course was uneventful.A pulmonary artery catheter recorded haemodynamic changes at the time of the venous air embolism. There was an initial increase in pulmonary artery pressure and central venous pressure, associated with a decrease in mean arterial pressure and oxygen saturation. Similar observations have been made in animal models of graded (infusion type) venous air embolism.The diagnosis of venous air embolism is generally clinical, aided by echocardiogram, end‐tidal carbon dioxide monitoring, pulse oximetry, chest radiography and haemodynamic monitoring. Current management of venous air embolism includes prevention of further air entry, positioning the patient head‐down in the left lateral decubitus position and administration of 100% oxygen. External cardiac massage, aspiration of air (via central venous catheter, pulmonary artery catheter or transcutaneously) and hyperbaric oxygen may also play a role.