VELscope: The challenge for the detection of orally potentially malignant lesions

Abstract

Early detection of oral cancer is crucial in improving survival rate; Identification and detection of oral potentially malignant disorders (OPMD) allow delivery of interventions to reduce the evolution of these disorders to malignancy. A variety of new and emerging diagnostic aids and adjunctive techniques are currently available to potentially assist in the detection of OPMD such as the autofluorescence technique.Pathologists utilize the autofluorescence approach to investigate body mucosa and screen for changes in tissue, which could lead to the earlier detection of pre-malignant, cancer, or other disease processes. Early identification is the most effective way to ensure treatment effectiveness, boost survival rates, and maintain a high quality of life. Autofluorescence examination of oral tissues using the VELscope has suggested as an adjunctive tool for cancer detection and diagnosis. The aim of our study was to evaluate the efficacy of the VELscope system autofluorescence to image the tissue of potentially malignant oral lesions. Also, to assess the diagnostic accuracy, sensitivity and specificity of this method.