Veloergometric Doppler study of brain blood circulation after balneological antler correction of vasomotor autoregulation

Abstract

The aim of the study was to evaluate the change in veloergometry (VEM)-induced dynamic state of peak blood flow velocity (Vps) and resistance index (RI) in the middle cerebral artery after balneotherapy of arterial hypertension with Altai red deer antlers.Material and methods. A small cohort of patients (n = 48) with grade I–II arterial hypertension aged 56 [50–59] years (median [lower quartile-upper quartile]) was examined. In the course of the duplex research of middle cerebra artery Vps, RI in a prone position, sitting and during a bicycle exercise were registered.Results. In a prone position Vps was 100 [95–105] сm/s, RI – 0.62 [0.58–0.64]; on the cycle ergometer Vps decreased by 20 % and was 80 [77–85] сm/s. In the course of bicycle exercises of average intensity (60 W for women and 90 W for men), Vps increased by 45 %, to 115 [112–120] сm/s, RI increased to 0.73 [0.71–0.75]. On a maximum excise loading Vps reduced by 25 % up to 88 [86–92] сm/s, RI did not change. After antler balneotherapy Vps in a prone position decreased and was equal 87 [82–92] сm/s (p = 0.0001), it occurred due to the improvement of microcirculation confirmed by decrease in RI to 0.52 [0.5–0.53] (р = 0.0001). To a lesser extent there was also an orthostatic falling of Vps at these patients. In the course of bicycle exercises of average intensity, Vps was registered with higher amplitude (up to 60 %, 122 [120– 125] сm/s). On a maximum of bicycle exercise Vps decreased by 30 % of an average and was equal to 85 [82–86] сm/s.Conclusions. Veloergometric Doppler study of a blood-groove in a middle cerebra artery is a representative method for assessing the dynamic state of autoregulation and can be used for diagnostic audit of physical therapy. The antler balneotherapy of the Altai maral products makes positive impact on cerebral vasomotor function.