Abstract
In recent years, textile industries have focused their attention on the development of functional finishing that presents durability and, consequently, controlled release. However, in the case of methyl salicylate microcapsules supported on a textile matrix, studies indicate only the interactions between substrate and microcapsules and the drug delivery system, not applying the release equations. This study reports the mechanism and kinetics of controlled release of microcapsules of gelatin and gum Arabic containing methyl salicylate as active ingredient incorporated into textile matrices. According to the results presented, it was possible to verify that the wall materials participated in the coacervation process, resulting in microcapsules with well-defined geometry, besides promoting the increase of the thermal stability of the active principle. The samples (100% cotton, CO, and 100% polyamide, PA) functionalized with microcapsules released methyl salicylate in a controlled manner, based on the adjustment made by the Korsmeyer–Peppas model, indicating a Fickian mechanism. The influence of temperature was noticeable when the samples were subjected to washing, since with higher temperature (50 °C), the release was more pronounced than when subjected to lower temperature (37 °C). The results presented in this study indicate that the mechanism of backbone release is influenced by the textile matrix and by the durability of the microcapsule during the wash cycles.
Highlights
Drugs, essential oils and fragrances have been used as essential compounds in textile finishing, in order to meet the various requirements that the consumer presents today
The interactions of the polymers used for the formation of the microcapsules were evaluated by the Functional Groups of the Microcapsules (FTIR) technique
The results presented above confirm that the encapsulation of methyl salicylate by complex coacervation microcapsules can significantly improve the thermal stability of the active compound, suggesting that it was encapsulated
Summary
Essential oils and fragrances have been used as essential compounds in textile finishing, in order to meet the various requirements that the consumer presents today. There are several microencapsulation techniques that can be used to improve the stability of the active ingredients, such as simple or complex coacervation, fluidization, lyophilization and spray drying [4,5] Among these techniques, complex coacervation is an alternative process, in which the ionic interaction between two polymers leads to the formation of coacervates and phase separation [6]. The treatment involves external application to the affected area of a drug that has methyl salicylate as its active ingredient It has some drawbacks, such as low water solubility and dosage control, as well as high volatility [18,19,20]. The present study aims to evaluate the behavior of methyl salicylate microcapsules obtained by complex coacervation and incorporated in Jersey 100% cotton and 100% polyamide textile structures, using in vitro release profiles, and when subjected to washing at different temperatures
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