Abstract

Introduction: Angiogenesis can be enhanced by several growth factors like VEGF165 and bFGF. A prolonged effect of protein based therapy is needed to induce stable capillary structures. Delayed release could be provided by incorporation of growth factors or other substances in slowly degrading fibrin matrices. In our work we are presenting a slow release system for VEGF165 and bFGF in fibrin sealant.

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