Vegetative Status with Arterial Hypertension in the Indigenous Population of the Far North and Migrants

Abstract

The increase of sympathetic activity can serve as a starting point for increase blood pressure for both humans and experimental animals. Activation of the sympathetic nervous system is important not only in the early stages of the disease but also contributes to the formation of the cardiovascular risk in life later. Comparative information about the vegetative status of indigenous people and migrants with hypertension in the Far North in a systematic scientific literature not presented. The purpose of this research was aimed for study of the dynamics of the vegetative status in patients with arterial hypertension in the Far North indigenous people and migrants. Condition of the autonomic nervous system by the residents of the Russian Far North with arterial hypertension was evaluated. The data using cardiointervalography and active orthostatic test in the indigenous population and migrants from Nadym district of the Tyumen region in the age of 18-60 years were obtained. The study involved 220 people working-age population (86 migrants and 134 indigenous peoples of the Far North). Among them are 41 patients with hypertension (26 migrants and 15 indigenous people). The average age of the surveyed migrants amounted to 40,1 ± 13,4 years for indigenous 37,8 ± 12,4 years. The duration of stay in the Far North for migrants was 14,9 ± 10,7 years. 5 options for autonomic tone, as well as differences in the autonomic nervous system disorders among migrants and indigenous peoples of the Far North with hypertension patients were installed. Violations of the autonomic nervous system for migrant are mild sympathicotonia coupled with significant impairment of vegetative support activities. It is typical for an unfavorable course of adaptation processes. For indigenous people the change reduces to a shift towards sympathicotonia without significant changes in vegetative support activities.