Vasotocin and Vasoactive Intestinal Polypeptide Modulate Aggression in a Territorial Songbird, the Violet-Eared Waxbill (Estrildidae:Uraeginthus granatina)

Abstract

Previous research demonstrates that intraseptal administrations of arginine vasotocin (AVT) inhibit male aggression in the territorial field sparrow (Emberizidae:Spizella pusilla) but facilitate aggression in the colonial zebra finch (Estrildidae:Taeniopygia guttata). In order to determine whether this difference may be related to the territorial and colonial social organizations of these two species, the effect of AVT infusions was examined in a territorial Estrildid species, the violet-eared waxbill (Uraeginthus granatina). This species is more closely related to the zebra finch than to the field sparrow and shares most critical features of breeding ecology in common with zebra finches, but differs in social organization. AVT infusions administered via chronic guide cannulae directed at the septum significantly inhibited aggressive behavior, consistent with results in the territorial field sparrow, supporting the hypothesis that social organization is correlated with AVT function. Similar experiments with mesotocin and substance P produced no effects on any of the behaviors measured, but infusions of vasoactive intestinal polypeptide (VIP) significantly facilitated aggression. This result contrasts with the inhibitory effect of septal VIP obtained in the colonial zebra finch, suggesting that VIP function may be correlated with social organization as well.