Abstract
Zygophyllum album has been mentioned in Tunisian system of traditional medicine to be of value in the treatment of diabetes mellitus. The aqueous extract from Zygophyllum album were examined for relaxant effects in isolated mice thoracic aorta, Nitric Oxide (N0) spin-trapping technique combined with Electron Paramagnetic Resonance (EPR) spectroscopy has been employed to measure the ex vivo production of NO in liver, heart, pancreas and aorta. The antihyperglycemic effects of aqueous extract from Zygophyllum album (100 and 300 mg/kg bw) during 15 days on important enzymes of carbohydrate metabolism in livers of non- diabetic and streptozotocin-induced diabetic mice was evaluated. Administration of the aqueous extract plant (100 and 300 mg/kg bw) for 15 days resulted in significant reduction in hepatic Glucokinase (GK), glycogen in STZ diabetic mice. In addition to that, significant increase in hepatic Phosphofructokinase (PFK), Glucose-6 Phosphate Dehydrogenase (G6PDH) observed in STZ diabetic mice.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
