Abstract
The use of vasopressors in the management of cardiac arrests seems at face value to be beyond question. Together with defibrillation, the maintenance of an adequate perfusion pressure to the heart and brain has long been deemed a priority of Advanced Cardiac Life Support protocols. To this end, the quest for the optimum vasopressor(s), drug and dose, has generated many laboratory studies and clinical trials. Indeed, the recent meta-analysis of studies of high-dose epinephrine for out-of-hospital resuscitation included over 6000 patients.
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