VASCULAR PROFILE IN PATIENTS WHO UNDERWENT CORONARY ANGIOGRAPHY WITH AND WITHOUT HYPERTENSION

Abstract

Abstract Objective: Assessment of vascular profile in women and men with and without hypertension who didn‘t have coronary artery stenosis in the angiography. Design and method: We divided 100 patients in two groups: HT+ patients with arterial hypertension (25 women and 25 men); and HT- patients without arterial hypertension (25 women and 25 men). All patients underwent coronary angiography because of angina. The average age of them [yrs]: 56 and 53 (∗p < 0,05). Ankle-brachial index (ABI), pulse wave velocity (PWV) and carotid intima-media thickness (IMT), BMI, uric acid were evaluated. Statistical calculations were performed in the StatSoft Statistica 10. For comparison of variables with a normal distribution and equal variances we used the t-test for unrelated samples. Results: We revealed following results in both groups: HT+ and HT- respectively [∗for p < = 0,05; ∗∗for p < 0,001; NS- negligible statistically]. In hypertensive group women were characterized by lower uric acid level, IMT and PWV than men. In normotensive group women were characterized by lower uric acid level than men Conclusions: 1. There was no difference in: ABI, PWV and IMT between the sexes in normotensive patients who underwent coronary angiography. 2. Women without stenosis in coronary angiography with and without hypertension were characterised by better metabolic profile than men. 3. Hypertensive women without stenosis in coronary angiography were characterized by minor vascular damages assessed by IMT and PWV than hypertensive men.