Abstract
Sporozoites of Sarcocystis cruzi penetrated various established cell lines but developed to meronts in bovine monocytes (BM) and bovine pulmonary artery endothelial cells (CPA) only. At 31 to 50 days after sporozoite inoculation, approximately four times more merozoites were harvested from cultures of CPA (72.7 × 106 merozoites) than from BM (16.6 × 106 merozoites). The ability to grow merogonous stages in vitro can now be used to elucidate pathogenetic and immunologic mechanisms associated with infection by Sarcocystis spp.
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