Vascular neovascularization and post-traumatic stress intervention of perforator flap obstruction in diabetic patients

Abstract

BackgroundDiabetic patients often suffer from neovascularization during branch flap repair, and the process of formation of these neo-vessels and post-traumatic stress intervention have not been adequately studied.Subjects and MethodsFifty diabetic patients were selected for this study and divided into an experimental group and a control group. The experimental group received post-traumatic stress intervention treatment, while the control group received conventional treatment. Choke vessels were counted and observed by collecting tissue samples from the study subjects using histological methods.ResultsData analysis software SPSS 23.0 was used for statistical analysis of data. A significant reduction in the number of Choke vessels was observed in the experimental group as compared to the control group (the mean number of Choke vessels was 10.2 in the experimental group and 17.8 in the control group, P<0.05). In addition, the blood glucose level of the experimental group was significantly decreased (the average blood glucose level of the experimental group was 8.6 mmol/L and the average blood glucose level of the control group was 11.4 mmol/L, P<0.01).ConclusionsPost-traumatic stress intervention can significantly reduce the number of Choke vessels and thus improve the results of perforator flap repair. It provides useful guidance for the surgical treatment of diabetic patients and provides an important theoretical basis for clinical practice.AcknowledgementThe research is supported by: the Hainan Provincial Natural Science Foundation of China (No. 821RC1064).