Abstract
To compare vascular injuries induced by a nonrotational thrombectomy device equipped with an adjustable basket (the AKónya Eliminator [AKE] device) and the Arrow-Trerotola percutaneous thrombolytic device (PTD) in porcine external iliac arteries (EIAs). The EIAs of nine domestic pigs underwent simulated thrombectomy with the AKE after the diameter of the basket had been adjusted to the vessel's diameter and with the PTD after motor activation. Three animals were euthanized immediately after treatment (group 1, acute), three after 1 week (group 2, subchronic), and three after 6 weeks (group 3, chronic). Vessel diameters were measured angiographically at four anatomic locations at the three time points. A histologic grading system was established to quantify the degree of vascular injury and lumen compromise. Four other EIAs were treated with an "oversized" AKE basket and followed for 6 weeks. Histologically, the acute lesions in the AKE-treated vessels were more superficial than those in the PTD-treated vessels. In group 2, two of three PTD-treated arteries occluded, and their subchronic injuries were more serious than those in the AKE-treated arteries. In group 3, all AKE-treated arteries remained patent, but one of the PTD-treated vessels occluded, and the lumen sizes of the PTD- and AKE-treated arteries differed significantly. After 6 weeks, there was no significant difference between arteries treated with the PTD and those treated with the oversized AKE in terms of diameter or histologic grading. The adjustable basket and hand-controlled operation of the AKE were significantly less injurious to the arterial wall than the constant-size PTD basket operated at 3,000 rpm. Damage produced by the oversized AKE basket was similar to that produced by the PTD.
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