Abstract
Introduction. To evaluate the role of hyperthermic isolated limb perfusion (HILP) in arterial thrombosis following melanoma-soft tissue sarcoma chemotherapy. Report. Here is presented one case of iliac-common femoral artery subacute thrombosis and a review of the appropriate literature performed using a MEDLINE search. Acute/subacute arterial occlusion is one of the most feared vascular complications of HILP, located nearly always in the external iliac-femoral artery axis, being those vessels cannulated for perfusion. Conclusions. The small number of reported cases indicates either the rarity of this complication or unawareness of its existence. The true incidence of this complication is probably underreported.
Highlights
To evaluate the role of hyperthermic isolated limb perfusion (HILP) in arterial thrombosis following melanomasoft tissue sarcoma chemotherapy
Acute/subacute arterial occlusion is one of the most feared vascular complications of HILP, located nearly always in the external iliac-femoral artery axis, being those vessels cannulated for perfusion
We here present a case of arterial thrombosis following hyperthermic isolated limb perfusion (HILP), a surgical procedure involving an open surgical cannulation of iliac or femoral vessels that is commonly employed in the management of some forms of malignant tumors as extremity sarcoma or melanoma
Summary
To evaluate the role of hyperthermic isolated limb perfusion (HILP) in arterial thrombosis following melanomasoft tissue sarcoma chemotherapy. Is presented one case of iliac-common femoral artery subacute thrombosis and a review of the appropriate literature performed using a MEDLINE search. Acute/subacute arterial occlusion is one of the most feared vascular complications of HILP, located nearly always in the external iliac-femoral artery axis, being those vessels cannulated for perfusion. The small number of reported cases indicates either the rarity of this complication or unawareness of its existence. The true incidence of this complication is probably underreported
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