Abstract

The effect of vascular implantation on the healing of free adipose tissue grafts was studied experimentally in rats. Adipose tissue resected from the parauterine pad was transplanted around the femoral vascular bundle. Two biological variants of the method were used: transplantation to (a) the freshly mobilized vascular bundle and (b) a bundle prepared three days previously. Implants made directly under the skin served as controls. Implantation around the freshly mobilized vascular bundle showed that healing of free adipose tissue implants is promoted by this technique: revascularization was augmented and the proportion of adipose tissue surviving was significantly greater than with the controls. With implantation into previously prepared tissue, there was evidence that healing may be further improved. The biological advantage thus gained was, however, largely impaired by the tissues being coated with fibrin; this prevented close contact between the graft and the recipient tissue.

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