Abstract

Cobb syndrome is an exceptional, non-inherited, genetic disorder characteristically constituted by vascular anomalies and neurological deficits. Spinal arteriovenous malformations appear in concurrence with cutaneous vascular lesions within the corresponding dermatome. Dermatome specific port wine stain upon the trunk, arteriovenous malformation, angioma, angiokeratoma, angiolipoma, cavernous haemangioma or lymphatic malformation is discerned in accompaniment with hyperreflexia, limb paresis, muscular cramps, sensory loss, bladder and bowel dysfunction, sudden paraplegia or subarachnoid haemorrhage. Spinal vascular lesions of Cobb syndrome can be adequately determined with magnetic resonance imaging (MRI), computerized tomography (CT) scan, plain radiography or angiography. Cobb syndrome can be appropriately managed with sclerotherapy, endovascular embolization, oral corticosteroids or surgical extermination of vascular lesions.

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