Varis dışı üst gastrointestinal sistem kanamalı hastaların demografik ve klinik özellikleri

Abstract

Background and Aims: Non-variceal upper gastrointestinal bleeding (NVUGB) is one of the most frequent emergencies. The aim of the present study was to determine the demographic and clinical features of NVUGB pa-tients. Materials and methods: Patients with NVUGB admitted between 2005-2010 years examined with endoscopy were evaluated retrospectively in terms of demographical characteristics, etiological risk factors, treatment mo-dalities and mortality.Results: Mean age of 228 (%77) male and 120 (%23) female was 59, 9 (17-99). 84 (%25.5) of the patients were smoking, 12 (%7) were drinking alcohol, 292 (%88.5) were using drug (148/292 (%44.8) non-steroidal anti-inflammatory drug (NSAIID), 113/292 (%34.2) acetyl salicylic acid. Hypertension (n=96, %29.1) was the most common comorbidty. En-doscopic procedure time: 156 (%47.3) in first 12 hours, 117 (%35.5) in first 12-24 hours, and 57 (%17.3) after 24 hours. Endoscopic therapy was perfor-med in 84 (%25.5) of the patients. Adrenalin injection was the most frequent treatment modality. Urease test was performed in 122 (%37) of the patients and 107 (%87) of this was helicobacter pylori positive. Patients were given 0.81±1.0 erythrocyte suspension at the first 12 hours, totally 1.8±2.1 eryt-hrocyte suspension were given.Conclusion: The most common causes of bleeeding were; 257 (%77.9) peptic ulcer, 119 (% 36.1) gastric ulcer, 203 (%61.5) and erosive gastritis. According to rockall score 61 (%18.5) patients had low risk, 260 (%78.8) patients had moderate risk and 9 (%2.7) patients had high risk. According to forrest score most of the patients had stage 3 ul-cer (n=153, %40.9) and stage 2B correlated with mortality positivley. Seven (%2.1) patients required surgical treatment and six (%1.8) patients died. Pep-tic ulcer was the most common cause of non-variciel upper gastrointestinal bleeding. Bleeding is seen more commonly in males and elders. Acetyl salicy-lic acid and NSAIID were found as risk factors in over half of the bleeding pa-tients. Rate of mortality, surgery and transfusion of erythrocyte suspension was very low. This might be related to the high rate of early endoscopy and endoscopical therapy.