Abstract

Varicose veins of the lower extremity (VVLE) are a frequently encountered vascular disorder in the general population. The general view that VVLE are a non-serious disease with primarily aesthetic impact is a common misconception, as the disease can have a significant negative impact on generic and disease-specific quality of life. Further, VVLE may be associated with potentially threatening clinical conditions, such as chronic venous ulceration, venous thromboembolism and haemorrhage from ruptured varicose veins. In the case of symptomatic varicose veins, in the presence of advanced lower limb skin changes or when venous complications occur, a referral for dedicated evaluation by the vascular medicine specialist is recommended. The initial diagnostic test of choice to detect the extent of the varicose disease and to plan treatment is duplex ultrasound. Traditionally, compression therapy, surgical high ligation and stripping of the truncal veins have been considered standard of care for VVLE. Driven by the aim to reduce surgical trauma and improve the long-term effectiveness, minimally invasive treatment options have been developed in the last two decades, namely endovascular vein ablation techniques (EVA). Endovenous laser ablation and radiofrequency ablation have been established as first-line treatments for varicose veins associated with axial reflux on the basis of the most recent international guidelines. For practical purposes and depending on the concrete clinical situation, the various EVA and surgical techniques are often combined, leading to multimodal varicose vein therapy management. Knowledge of the different techniques is of utmost importance for the vascular medicine specialist. The purpose of this article is to provide an overview of the new EVA techniques and to elucidate the different therapeutic strategies for VVLE.

Highlights

  • Varicose veins are a manifestation of chronic venous dysfunction [1]

  • The general view that Varicose veins of the lower extremity (VVLE) are a non-serious disease with primarily aesthetic impact is a common misconception, as the disease can have a significant negative impact on generic and disease-specific quality of life

  • VVLE may be associated with potentially threatening clinical conditions, such as chronic venous ulceration, venous thromboembolism and haemorrhage from ruptured varicose veins

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Summary

Introduction

Varicose veins are a manifestation of chronic venous dysfunction [1]. In a consensus statement from the American Venous Forum, varicose veins are defined as subcutaneous, usually tortuous and dilated veins, 3 mm or larger in diameter as measured in the upright position. In the course of the disease the superficial leg veins change in morphology and become varicose. If appropriate management is not initiated, a series of changes in the skin and subcutaneous tissue occur as a result of the venous hypertension. These changes can include tissue oedema, skin hyperpigmentation, lipodermatosclerosis (induration caused by fibrosis of the subcutaneous fat), eczematous dermatitis, atrophy blanche (white scar tissue) or venous ulceration [10]. More threatening complications include haemorrhage from a ruptured varicose vein [11] as well as superficial varicophlebitis with the possible development of deep vein thrombosis with or without pulmonary embolism [12]. Associated symptoms in patients suffering from varicose veins are itching, feeling of heaviness, tightness, swelling and pain

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