Abstract
BackgroundChorioretinitis is an unusual form of varicella zoster virus (VZV)-associated uveitis, and no report has described VZV-associated chorioretinitis using serial optical coherence tomography (OCT) images obtained during the course of resolution.Case presentationA 61-year-old woman presented with acute, unilateral vision loss in her right eye. Her visual acuity was count fingers in the right eye and 16/20 in the left eye, and she exhibited skin vesicles on her right forehead. Slit lamp biomicroscopy, funduscopy, OCT, and intraocular fluid analysis were performed. The right eye exhibited multiple inflammatory lesions at the posterior pole, macular edema, and disc swelling on the fundus examination. OCT revealed predominant involvement of the choroid and the retinal pigment epithelium (RPE). Intraocular fluid analysis showed positivity for VZV. The patient was admitted and treated with intravenous acyclovir. Additional oral prednisolone was used to reduce the inflammatory reaction. After 2 weeks of treatment with acyclovir, the lesion resolved, with undulation of the RPE. Her final visual acuity was 20/20.ConclusionsVZV-associated posterior uveitis may present as multifocal chorioretinitis. Intraocular fluid analysis is important to detect an infectious origin.
Highlights
Chorioretinitis is an unusual form of varicella zoster virus (VZV)-associated uveitis, and no report has described VZV-associated chorioretinitis using serial optical coherence tomography (OCT) images obtained during the course of resolution.Case presentation: A 61-year-old woman presented with acute, unilateral vision loss in her right eye
VZV-associated posterior uveitis may present as multifocal chorioretinitis
We described an unusual presentation of VZVassociated uveitis with exudative retinal detachment in an elderly woman
Summary
Varicella zoster virus (VZV) may involve the posterior segment of the eye and is an important cause of acute retinal necrosis (ARN), which is characterized by rapidly progressing peripheral necrotizing retinitis and a prominent inflammatory reaction in the vitreous/anterior chamber [1]. VZV has been associated with the non-ARN type of posterior uveitis or multifocal posterior necrotizing variants [2, 3]. We describe a case of VZV-associated chorioretinitis using multimodal images. Case presentation A 61-year-old woman presented with acute vision loss in her right since 1 day. Her medical history included hypertension, cerebral aneurysm, and Alzheimer’s dementia. She was on oral acyclovir for herpes zoster infection involving
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