Abstract
Abstract Varicella zoster virus (VZV), also known as human herpes virus 3 (HHV3), causes varicella (chicken pox) upon primary infection, establishes latency in dorsal root ganglia (DRG) and can later reactivate to cause herpes zoster (shingles). Difficulties in studying the pathogenesis of VZV; because of its high cell association and narrow host range, have been overcome through the development of the VZV severe combined immunodeficient (SCID) mouse model carrying human tissue implants. VZV is the first human herpes virus for which a live attenuated vaccine has been developed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
