Variations in the amount of saline extractable collagen in skin distant to a healing wound

Abstract

<h2>Summary</h2> The amount of saline extractable collagen in the center of an incised and sutured wound and in strips of skin 7 mm. distant from the wound, from the lateral thoracic wall and from the ventral abdominal wall have been determined during periods immediately following wounding and during maximum collagen production in the center of the wound. Analysis of the data revealed an early sustained increase in saline extractable collagen in skin 7 mm. from the skin edge, a small significant rise in saline extractable collagen in skin from the lateral thoracic wall, and an insignificant elevation of saline extractable collagen in ventral abdominal skin during periods of elevated saline extractable collagen in the center of the wound.