Abstract

Globally, the incidence of obesity is known to be linked to a number of other riskfactors such as diabetes, cardiovascular disease, amongst others, however, there are population specific variance and severity. Therefore, this study t investigated the possible variations in glycosylated haemoglobin (HbA1c) levels of obese women resident in Rivers State, Nigeria. Precisely, 334 obese and non-obese women within the ages of 18 and 65 years with no obvious health challenge and resident in Upland and Riverine areas of Rivers State were actually surveyed by the present study. A multistage sampling technique was adopted, and subjects were surveyed across the upland and riverine locations of the State. These subjects were evenly drawn from the multi-ethnic residents of the state. Anthropometric (body mass index- BMI) data and blood sample (via antecubital vein following standard procedures) were obtained from the consenting subjects. After laboratory analyses, the quantitative data got were subjected to statistical analyses using the statistical package for social sciences (SPSS) version 21.0. One-way analysis of variance (ANOVA) and independent t-test with a p< 0.05 considered statistically significant were determined. The result also revealed that all obese subjects as well as their UPL and RVR subgroups had significantly (P<0.05) elevated HbA1c compared to their respective non-obese groups and these increases were both graded and marked (P<0.05) with increasing BMI. It is also important to note that the non- obese and obese class III of the RVR subjects had markedly (P<0.05) higher levels when compared to those of their UPL counterparts.The finding of this study on the changes in HbA1c levels of obese women resident in UPL and RVR residents revealed significant (P<0.05) rising percentages of HbA-1c with increasing BMI. It can thus be concluded that the incidence of obesity and associated comorbidities are substantially linked to sex, ethnic/culture and socioeconomic status.

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