Variations hémorhéologiques au cours de 50 dysglobulinémies monoclonales traitées par échanges plasmatiques

Abstract

Rheological examinations were performed before and after plasma exchanges in 50 patients with monoclonal dysglobulinaemia. The parameters investigated were blood and plasma viscosity, erythrocyte filtrability, erythrocyte aggregation and kinetics of agglutination. The results showed reduction of blood and plasma viscosity and improvement in agglutination kinetics under plasma exchanges. Rheological examinations therefore seem to be useful to follow up blood disorders, notably the hyperviscosity syndrome. They can be performed prophylactically, leading to early plasma exchanges to prevent clinical deterioration.