Abstract
BackgroundThe prolongation of repolarization time between the myocardial epicardium and endocardial cells is closely related to malignant ventricular arrhythmias. The purpose of our study was to compare repolarization markers, namely, T‐wave peak‐end interval (Tp‐e), QT, corrected QT (QTc), Tp‐e/QT, Tp‐e/corrected QT (QTc), and Heart Rate Variability (HRV) values in healthy men and women and to investigate their daily variations.MethodsA total of 74 male and 78 female participants, being a government employee, and having no health problems, were included in the two study groups (males and females). A 24‐hour, 12‐lead Holter monitoring was performed on the volunteers. Then, the Tp‐e interval and QT interval were measured on recordings. cTp‐e and QTc were calculated by the use of Bazzet's formula.ResultsThere was no statistically significant difference between the groups in the cTp‐e interval at 07.00 pm; however, it was significantly lower in the female group as compared with the male group at 07.00 am and 01.00 pm. It was significantly higher in the female group at 01.00 am compared with the male group. There were statistically significant moderate negative correlations between Tp‐e intervals and a standard deviation of between two normal beats interval (SDNN) values at various hours of the same day.ConclusionThere were statistically significant differences in terms of Tp‐e and cTp‐e intervals at various hours of the same day in both groups. In addition, there were statistically significant moderate negative correlations between Tp‐e intervals and SDNN at various hours of the same day.
Highlights
Cardiovascular system-related deaths are still the most common cause of death in both men and women worldwide
There is a general decrease in Heart Rate Variability (HRV) with age and deterioration of autonomic balance against vagal tonus, but still more sympathetic tonus in men of the same age group than women.[4]
We found different repolarization markers with different values in healthy men and women at different times on the same day
Summary
Cardiovascular system-related deaths are still the most common cause of death in both men and women worldwide. The purpose of our study was to compare repolarization markers, namely, T-wave peak-end interval (Tpe), QT, corrected QT (QTc), Tp-e/QT, Tp-e/corrected QT (QTc), and Heart Rate Variability (HRV) values in healthy men and women and to investigate their daily variations. Results: There was no statistically significant difference between the groups in the cTp-e interval at 07.00 pm; it was significantly lower in the female group as compared with the male group at 07.00 am and 01.00 pm It was significantly higher in the female group at 01.00 am compared with the male group. There were statistically significant moderate negative correlations between Tp-e intervals and a standard deviation of between two normal beats interval (SDNN) values at various hours of the same day. Conclusion: There were statistically significant differences in terms of Tp-e and cTp-e intervals at various hours of the same day in both groups. There were statistically significant moderate negative correlations between Tp-e intervals and SDNN at various hours of the same day
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