Abstract

BackgroundTo identify best practices and quality improvement initiatives, we aimed to assess whether the incidence of Periprosthetic Joint Infection (PJI) and treatment strategies differed across patients treated in Australian, European and United States (US) hospitals.MethodsRoutinely collected administrative data for 41397 patients undergoing a primary total hip or knee arthroplasty between July 2007-December 2010 across 22 hospitals were included. Patients were followed for 2 years looking for PJI occurrence, defined as early (within 4 weeks) and late PJI, and surgical treatment during 2.5 years after PJI diagnosis. Logistic and Poisson regression models were used to test for differences in PJI occurrence and treatment strategies across the three geographical regions, adjusted for age, sex, joint and Elixhauser comorbidity groups.ResultsPJI occurrence varied from 1.4% in European to 1.7% in Australian patients, which were significantly higher than US patients after adjustment for patient characteristics (OR 1.24 [1.01–1.52] and 1.40 [1.03–1.91] respectively). Early PJIs varied between 0.3% in European to 0.6% in Australian patients, but adjusted rates were similar. Revision following PJI was significantly lower in Australian than in US patients (OR 0.46 [0.25–0.86]) as were the total number of revisions (RR 0.51 [0.36–0.71]) and number of surgical procedures (RR 0.60 [0.44–0.81]) used to treat PJI.ConclusionThe overall PJI rate was significantly higher in Australian patients, but fewer procedures were needed to treat these PJIs. Future research should reveal whether this reflects PJIs caught earlier or less severe when diagnosed, and whether this is associated with the longer length of stay after primary arthroplasty in Australian hospitals.

Highlights

  • To identify best practices and quality improvement initiatives, we aimed to assess whether the incidence of Periprosthetic Joint Infection (PJI) and treatment strategies differed across patients treated in Australian, European and United States (US) hospitals

  • Crude PJI rates were highest in Australian patients (1.7%) and lowest in Europe (1.4%)

  • What the present study has shown for the first time is that both PJI diagnosis and the associated treatment strategy seem to differ across patients treated in different health care systems

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Summary

Introduction

To identify best practices and quality improvement initiatives, we aimed to assess whether the incidence of Periprosthetic Joint Infection (PJI) and treatment strategies differed across patients treated in Australian, European and United States (US) hospitals. The number of arthroplasties is expected to increase considerably over the decades, [3, 4] due to the ageing population, an increasing prevalence of obesity, and the demand and expectation of these procedures in increasingly younger patients [5]. This increased burden on our healthcare systems will have considerable societal and economic consequences [6]. PJI rates may vary, between hospitals and between health care systems, and with respect to treatment strategies used By studying these variations, we may be able to identify best practices and directions for quality improvement. With the expected growth in THA and TKA procedures to be performed in the coming decades, the rise in antimicrobial resistance of organisms and the increased complexity of patients being cared for, the number of PJIs is likely to increase along with significant costs to treat PJI [11, 14]

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