Abstract

Variation in physiological function within and between menstrual cycles: uncovering the contributing factors.

Highlights

  • Link: Northumbria University has developed Northumbria Research Link (NRL) to enable users to access the University’s research output

  • Studies investigating hormonal influences at a cellular level demonstrate large, and often distinct effects of key sex hormones, such as oestrogen and progesterone, whereas in contrast, in vivo studies into physiological function across the menstrual cycle in humans often show heterogeneity in reported outcomes. One example of this is the assessment of vascular function via flow mediated dilatation (FMD), with a recent systematic review and meta-analysis by Williams et al (2020) highlighting considerable heterogeneity between studies investigating the change in FMD across the menstrual cycle

  • It is thought that much of the heterogeneity in menstrual cycle research can be explained by methodological differences between studies

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Summary

Introduction

Link: Northumbria University has developed Northumbria Research Link (NRL) to enable users to access the University’s research output. Correspondence Paul Ansdell, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK. One example of this is the assessment of vascular function via flow mediated dilatation (FMD), with a recent systematic review and meta-analysis by Williams et al (2020) highlighting considerable heterogeneity between studies investigating the change in FMD across the menstrual cycle.

Results
Conclusion

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