Abstract
Male and female rats of Maudsley Reactive and Non-Reactive, Roman High and Low Avoidance strains were injected with either 0.8 mg/kg dose of nicotine bitartrate or distilled water. Nicotine facilitated rearing frequency. Strain differences were found. The Roman High Avoidance and Non-Reactive strains were more sensitive to nicotine than their counterparts. Female rats were found to be superior to the males in rearing score.
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