Abstract
Among adults using medical cannabis frequently and recently, THC and CBD metabolite concentrations in urine often differed from expected exposure. Approximately one-third of samples from people reporting using CBD-dominant products contained no measurable CBD metabolite. Nearly 1 in 5 samples from those using vaped cannabis contained no detectable cannabinoids....
Highlights
A growing market of medical cannabis products claim to have specific Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) content, but regulation of THC and CBD content is inconsistent across states and generally weak.[1]
Ninety-seven participants provided 256 urine samples meeting the criteria for analysis
At least 1 cannabis metabolite was detected in 220 samples (85.9%) (Table 1)
Summary
A growing market of medical cannabis products claim to have specific Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) content, but regulation of THC and CBD content is inconsistent across states and generally weak.[1]. To examine the association between medical cannabis product use and exposure to THC and CBD, we quantified levels of THC, CBD, and their metabolites in urine of participants in a clinical trial (ClinicalTrials.gov identifier NCT03224468) of medical cannabis in Massachusetts.
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