Abstract

Squamous cell carcinoma (SCC) is a malignant epithelial neoplasm exhibiting squamous differentiation as characterized by the formation of keratin and/or the presence of intercellular bridges. The epidermoid carcinoma is the most common malignant neoplasm of the oral cavity which also certain histopathological variations. The present review article focuses on histopathological variations seen in SCC along with brief emphasis on the biomarkers and prognostic factors which help in accurate diagnosis of SCC.

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