Abstract
Vitamin D deficiency is recognized as a global public health problem, with deficiency states reported from various countries. Acting as a Pro-Hormone; this is a unique endogenously synthesized vitamin. Besides its pivotal role in calcium homeostasis and bone mineral metabolism, the vitamin-D endocrine system is now recognized to sub-serve a wide range of fundamental biological functions in cell differentiation, inhibition of cell growth, and immunomodulation. Vitamin-D deficiency affects not only musculoskeletal health but also a wide range of acute and chronic disease.
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