Abstract

This review deals with variability of arterial pressure (VAP) as an advers factor contributing to the development andprogression of cardiovascular diseases and renal pathology. VAP has recently attracted much attention in connection with results of ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) showing that VAP is a risk factor of stroke and other complications of arterial hypertension (A H). The relationship between VAP and renalfunction remains unexplored and is considered to be a vicious circle in which kidneys are both a cause of AH and its target organs. Evidently elucidation of the relationship between enhanced VAP and renal function is of primay importance.

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