Abstract
Varenicline (Chantix) is effective for achieving smoking cessation. However, since 2009, the FDA has required a black box warning on varenicline about possible neuropsychiatric adverse events. In this meta-analysis of 39 randomized controlled trials (duration, 1–52 weeks) that involved 11,000 long-term smokers (average use, 20 cigarettes daily for 26 years), …
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