Abstract
Oxidation is a natural part of the aerobic world. Usually oxidation is suppressed by adding various antioxidants. Although a huge amount of antioxidants is known, studies of more active antioxidants which could be used in smaller amounts are crucial. Previously we have demonstrated arylmethyl Meldrum`s acids as promising free radical scavengers. On the other hand various phenol type compounds represent one of the most diverse group of antioxidants. In this study, two types of antioxidants – 1,3-dicarbonyl and phenol – were combined in a single molecule to study the plausible synergistic effects. Vanillic acid was used as a phenolic antioxidant, and Meldrum’s acid was the 1,3-dicarbonyl type antioxidant. The target compound was synthesized in four steps, and its antiradical activity was assessed using the DPPH method. The antiradical activity of the synthesized antioxidant was higher than that of widely used BHT.
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