Abstract
Antibiotic resistant bacteria are a growing public health concern and inappropriate antibiotic use is the primary, modifiable driver of this trend. Vancomycin has been the gold standard for treating serious infections due to methicillin-resistant Staphylococcus aureus (MRSA) for decades. Optimizing the use of vancomycin is critically important as over 30 vancomycin-resistant S. aureus strains have already been identified. Studies examining vancomycin use in the ED have reported inappropriate use rates as high as 90%. However, these studies utilized appropriate use criteria that do not accurately reflect current antibiotic use practices in the ED, especially regarding patients with suspected sepsis.
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