Abstract

Vancomycin Heteroresistance in Methicillin-resistant<i>Staphylococcus aureus</i>, Taiwan

Highlights

  • To the Editor: In 1997, Hiramatsu and colleagues reported the first clinical isolate of methicillin-resistant Staphylococcus aureus (MRSA) showing reduced susceptibility to vancomycin [1]

  • methicillin-resistant Staphylococcus aureus (MRSA) bacteremia relapsed in November 2001, and the patient received intravenous teicoplanin treatment (400 mg every 2 days) for 3 weeks, and fever resolved rapidly

  • MICs of vancomycin were determined for the 21 isolates of MRSA from the two patients (Table) by the broth microdilution and agar dilution method using brain-heart infusion (BHI) agar or broth and MuellerHinton agar (MHA) or broth (BBL Microbiology Systems, Cockeysville, MD), according to the recommendations by the National Committee for Clinical Laboratory Standards [5]

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Summary

Introduction

To the Editor: In 1997, Hiramatsu and colleagues reported the first clinical isolate of methicillin-resistant Staphylococcus aureus (MRSA) showing reduced susceptibility to vancomycin [1]. MRSA bacteremia relapsed in November 2001, and the patient received intravenous teicoplanin treatment (400 mg every 2 days) for 3 weeks, and fever resolved rapidly.

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