Abstract
Van Wyk–Grumbach syndrome is a rare presentation of long-standing prepubertal hypothyroidism in a female characterized by bilateral polycystic ovaries, delayed skeletal growth, and isosexual precocious puberty. We report a case of juvenile primary hypothyroidism presenting as an abdominal mass due to huge bilateral ovarian cysts which responded to the thyroid hormone replacement therapy. This case report highlights that hypothyroidism and other endocrinopathies should be considered in the differential diagnosis of girls with short stature and ovarian masses to avoid unnecessary surgery in young women.
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