Abstract

Abstract The method used previously for the study of the Van der Waals-London interactions in hydrogen bonded purine and pyrimidine pairs Pullman, Claverie & Caillet 1966 has been extended to a similar investigation of the interactions between “stacked” bases. Three problems have been considered: the interaction of free bases or their nucleosides in aqueous solution, the interaction of the bases in oligo- and polynucleotides and the interaction of the base-pairs in DNA. Calculations have been carried out in the “monopole” approximation.

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