Abstract
To investigate the value of ultrasound elastography (UE) in the differentiation between benign and malignant enlarged cervical lymph nodes (LNs). B-mode ultrasound, power Doppler imaging and UE were examined to determine LN characteristics. Two kinds of methods, 4 scores of elastographic classification and a strain ratio (SR) were used to evaluate the ultrasound elastograms. The cutoff point of SR had high utility in differential diagnosis of benign and malignant of cervical lymph nodes, with good sensitivity, specificity and accuracy. UE is an important aid in differential diagnosis of benign and malignant cervical LNs.
Highlights
The reasons of enlarged cervical lymph nodes (LNs) can be metastasis, reactivity, primary malignance and tuberculosis
Ultrasound elastography was evaluated by stiffness of lesions and surrounding normal tissues to judge the nature of lesions
The stiffness of the lesions was determined by its aspects of pathology character, such as cell types of lesions, the proportion of all kinds of cells and level of metabolic, micro and macro pathological structure, etc
Summary
The reasons of enlarged cervical LNs can be metastasis, reactivity, primary malignance and tuberculosis. Overall, it can be divided into benign and malignant enlargement. The purpose of this study was to investigate the value of UE in the differentiation between benign and malignant enlarged cervical lymph nodes. To investigate the value of ultrasound elastography (UE) in the differentiation between benign and malignant enlarged cervical lymph nodes (LNs). Results: The cutoff point of SR had high utility in differential diagnosis of benign and malignant of cervical lymph nodes, with good sensitivity, specificity and accuracy. Conclusion: UE is an important aid in differential diagnosis of benign and malignant cervical LNs.
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