Abstract
Objective To investigate the value of the preoperative Child-Pugh score and albumin-bilirubin (ALBI) score predicting posthepatectomy liver failure (PHLF) and prognosis of patients with hepatocellular carcinoma (HCC). Methods The retrospective cohort study was conducted. The clinical data of 226 HCC patients who were admitted into the People′s Hospital of Peking University between January 2010 and October 2014 were collected. After preoperative related examinations, feasibility and extent of liver resection were discussed according to patients′ conditions by multidisciplinary team, and then surgery was performed. Observation indicators: (1) surgical situations; (2) factors analysis affecting PHLF of HCC patients; (3) receiver operating characteristic (ROC) curve analysis of Child-Pugh and ALBI scores predicting PHLF; (4) follow-up and survival situations; (5) prognosis analysis of HCC patients after hepatectomy. Follow-up using outpatient examination and telephone interview was performed to detect postoperative survival up to August 2016. Measurement data with normal distribution were represented as ±s. Measurement data with skewed distribution were described as M (P25, P75). The survival curve was drawn by the Kaplan-Meier method, and the Log-rank test was used for survival analysis. The influencing factors of PHLF were analyzed using the logistic regression model. The prognostic factors were analyzed by the COX regression model. ROC analysis was used for predictive value of Child-Pugh and ALBI scores. Results (1) Surgical situations: 226 patients underwent successful surgery, including 171 receiving localized liver resection ( 0.05). Conclusion Preoperative ALBI score in predicting PHLF is superior to that of Child-Pugh score, but ALBI score is not independent factor affecting prognosis of HCC patients. Key words: Hepatic neoplasms; Child-Pugh score; Albumin-bilirubin score; Posthepatectomy liver failure; Prognosis
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
