Abstract
The in vitro reduction of NBT dye by polymorphonuclear cells was tested for use as an additional means for determining the presence of bacterial sepsis in forty general surgical patients. In four surgical settings the NBT dye test proved valuable: (1) in defining the presence of postoperative septic complications; (2) in distinguishing among bacterial, viral, and malignant causes of abdominal pain; (3) in differentiating between fever caused by sepsis and that caused by metastatic disease in cancer patients; (4) in evaluating the effect of surgical drainage and antibiotic treatment in septic surgical patients. This test was performed easily by physicians and technicians and was reproducible.
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