Value of serum procalcitonin and cardiac troponin I detection in predicting prognosis of acute myocardial infarction

Abstract

Objective To investigate the value of serum procalcitonin (PCT) and cardiac troponin I (cTnI) detection in predicting prognosis of acute myocardial infarction (AMI). Methods A total of 160 AMI patients treated in Shanxi Cardiovascular Hospital from October 2017 to October 2018 were selected as the observation group, and they were further divided into major adverse cardiovascular events (MACE) group (52 cases) and non-MACE group (108 cases) according to occurrence of MACE during 6-month follow-up. And 131 persons underwent physical examination in the hospital were selected as the control group. The PCT and cTnI levels were compared between the control group and observation group. The correlation of PCT and cTnI levels with MACE was analyzed by Spearman analysis. The receiver operating characteristic (ROC) curve was used to evaluate the value of PCT and cTnI in predicting prognosis of AMI. Results The serum PCT and cTnI levels in the observation group were significantly higher than those in the control group (P 0, P<0.05). ROC curve analysis showed that area under ROC curve, sensitivity and specificity of serum PCT were 0.682, 33.3% and 98.1%, respectively; while those indexes of serum cTnI were 0.710, 90.7% and 57.7%, respectively. The detection of PCT and cTnI had good predictive value for prognosis of AMI patients (P<0.05). Conclusions Serum PCT and cTnI levels in patients with AMI are positively correlated with the occurrence of MACE, which can be used to evaluate the prognosis of patients. Key words: Procalcitonin; Prognosis; Cardiac troponin I; Acute myocardial infarction