Value of right ventricular dimensions\u2019 swings on weaning from mechanical ventilation

Abstract

BackgroundCardiac dysfunction is a common cause of weaning failure. Previous studies focused on the role of LV diastolic dysfunction in the occurrence of weaning failure, and there are no more studies yet interested in RV dysfunction.Herein we evaluate cardiac changes using tissue Doppler echocardiography in critically ill patients during the weaning process and to compare between left and right ventricular functions as a predictor of weaning failure from mechanical ventilation.MethodsWe recruited 40 mechanically ventilated patients admitted to our ICU in this cross-sectional study. Echocardiography was performed during baseline ventilator settings and during spontaneous breathing trial (SBT) to assess changes in cardiac dimensions and functions. of left and right ventricular contractility and relaxation in this subset of patients.ResultsAmong 40 patients included, there was a significant increase in cardiac dimensions during SBT. There was a statistically significant decrease in LV EF with (P=0.000) during SBT. Also, there was a statistically significant decrease in RV systolic function during SBT. There was a significant increase in the E/E′ ratio of lateral mitral annulus due to the evolution of impaired LV relaxation and diastolic dysfunction (P=0.008). Moreover, the development of right ventricular diastolic dysfunction presented by E/E′ ratio of tricuspid annulus, (P value=0.03).ConclusionsRV dysfunction, as detected by systolic wave velocity of anterior tricuspid annulus (S′) by Doppler tissue imaging during SBT, also has good sensitivity and specificity in weaning failure prediction from mechanical ventilation.