Abstract
Reticulocyte count performed on a supravitally stained blood film is a initial and common laboratory method of determining early hematological recovery. This method is rapidly replaced by automated flow cytometry methods which have the advantage of much greater precision, before other test become positive after chemotherapy. A prospective observational study was carried out in the Department of Laboratory Medicine in collaboration with Paediatric Haematology and Oncology, Bangabandhu Sheikh Mujib Medical University during a period of one year to evaluate the bone marrow recovery in children with acute lymphoblastic leukemia by automated reticulocyte analysis over platelet count. Total fifty patients were enrolled in this study on remission induction phase. All patients were between 8 months to 15 years’ age range with a mean age of 5.5 ± 3.2. At the end of the study out of 50 cases, Ret% and Abs ret count showed early recovery in a median of 6 days before the platelet count recovery and concluded that reticulocyte parameter showed earlier haematopoietic recovery than the platelet count recovery.
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