Abstract
Objective To evaluate the diagnostic efficacy of the pulmonary perfusion tomography combined with low dose CT scan (Q SPECT/CT) in detecting acute pulmonary embolism (PE) by comparing with pulmonary ventilation/perfusion (V/Q) SPECT imaging. Methods A total of 203 patients suspected with acute PE (88 males, 115 females, age range 19-94 years) from January 2013 to December 2015 were enrolled in this retrospective study. All patients underwent V/Q SPECT and low dose CT scan. Final clinical diagnosis was regarded as the gold standard. The diagnostic consistency and diagnostic efficacy of Q SPECT/CT were compared with those of V/Q SPECT. χ2 test was used to compare the differences between the two methods. Kappa analysis was used to analyze the agreement of them. Results The coincidence rate of Q SPECT/CT and V/Q SPECT was 94.09%(191/203), Kappa=0.882, P 0.05). Conclusion In the majority of patients with suspected acute PE, V/Q SPECT scan can be replaced by Q SPECT/CT, but it must be careful to select Q SPECT/CT for patients with COPD history. Key words: Pulmonary embolism; Tomography, emission-computed, single-photon; Tomography, X-ray computed; Technetium; Technetium Tc 99m aggregated albumin
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