Value of procalcitonin levels, white blood cell count combined with nine-item assay for combined detection in diagnosis of respiratory tract diseases

Abstract

Objective To investigate the value of procalcitonin (PCT) levels, white blood cell count(WBC) combined with nine-item assay for combined detection (NACD) in diagnosis of respiratory tract infections(RTI). Methods From January 2014 to December 2015, 435 RTI patients were randomly selected.According to original body category, the patients were divided into bacteria infection group (n=185) and non-bacteria infection group (n=250). The IgM antibody and phlegm training positive rates, serum PCT levels, and WBC counts, serum PCT levels, and WBC counts separate detection and joint detection of sensitive degrees, and specific degrees, different type IgM antibody infection disease original body distribution were analyzed. Results The positive rate of bacterial infection in sputum culture (41.62%) was higher in bacteria infection group than that in non-bacterial infection group (7.60%), IgM antibody positive rate (9.73%) was less than that in the non-bacterial infection group (54%), there were significant differences (P<0.05). The serum PCT levels and WBC counts were higher in bacteria infection group than those of non-bacterial infection group, there were significant differences (P<0.05). The single specificity, sensitivity of serum PCT level, WBC count detection was lower than those of the combined PCT, WBC count detection, and there were significant differences (P<0.05). The original body of different type IgM antibody infection was as the follows, pneumonia accounting for 62.09%, Deputy flu virus accounting for 10.46%, and respiratory collection cell virus accounting for 8.5%, and addicted to lung Regiment bacteria serum I type accounting for 7.84%, and b type flu virus accounting for 7.84%, and pneumonia clothing original body accounting for 3.92%, and gland virus accounting for 2.61%, and Q hot rickettsia accounting for 1.96%. Conclusions The combined detection of PCT, WBC and NACD in the diagnosis of RTI, can improve the clinical diagnosis rate, accurately determine the types of pathogens, has great value in clinical appropriate selection and use of drugs, avoid overuse of antibiotics. Key words: Pocalcitonin; White blood cell count; Nine-item assay for combined detection; Bacterial cultures; Respiratory tract infection