Value of MRI in Differentiation between Benign and Malignant Breast Mass

Abstract

Objectives: This study aimed to evaluate the role of MRI in differentiation between benign and malignant well-circumscribed breast masses.
 Methods: A prospective cross-sectional study conducted on selected female patients with Breast mass who their age older than 35 years. All patients underwent examination using 1.5 Tesla magnetic resonance unit (MAGNETOM AERA, SIMENS).
 Results: 30 female patients were selected (mean age of 44.2±9.2 years, range between 35-69). Final findings of MRI revealed that 6 (20%) women had malignant breast mass while 24 (80%) women had benign breast mass. The histopathology revealed that 4 (13.3%) women were having malignancy while 26 (86.6%) were having benign breast tumor. There was a highly significant association between malignancy and hyperdense mammography findings of women (p<0.001), multiple lymph nodes for women (p<0.001), increased size of mass by MRI (p<0.001), circumscribed macrolabular lesion on MRI, rapid early kinetic phase of enhanced MRI (p<0.001), washout late kinetic phase enhanced MRI (p<0.001), and MRI kinetic curve type 3(p<0.001). There was a highly significant association between homogenous enhanced MRI findings of women and benign lesions (p<0.001).
 Conclusion: The validity results of MRI in differentiation between benign and malignant circumscribed breast masses are high, except for positive predictive value, and application of kinetic curve dynamic contrast enhancement increases magnetic resonance in differentiation between benign and malignant circumscribed breast masses.