Abstract
Objective To investigate the value of interferon-γ release assays(IGRAs)in early diagnosis of pneumoconiosis complicated with tuberculosis. Methods The retrospective study analyzed the results of IGRAs of 498 patients with pneumoconiosis at our hospital from January 2016 to December 2017.The results were compared with those of 1176 non-pneumoconiosis patients. Results The rate of positive IGRAs in patients with pneumoconiosis who had symptoms of respiratory infection was 33.73%, significantly higher than that in non-pneumoconiosis patients(23.64%)(χ2=18.24, P<0.0001). In pneumoconiosis patients with tuberculosis, the rate of positive IGRAs was 95.35%, and in pneumoconiosis patients without tuberculosis, the rate was 89.13%(χ2=0.48, P=0.49). The rates of positive IGRAs in patients with stage Ⅱ and stage Ⅲ pneumoconiosis were significantly higher than those in the patients with stage Ⅰ pneumoconiosis, and they increased with the progression of pneumoconiosis(χ2=2.21, P=0.023). Conclusions IGRAs offer added diagnostic value in early diagnosis of pneumoconiosis complicated with tuberculosis. Key words: Interferon-gamma; Pneumoconiosis; Tuberculosis, Pulmonary
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
