Abstract
胰腺癌是一种恶性程度极高的肿瘤,近年来其患病率在全球范围内呈上升趋势,在美国每年新发现病例约28000人,居恶性肿瘤死亡原因的第4位,胃肠道肿瘤死亡原因的第2位.由于胰腺癌位置隐秘,症状不典型,一旦确诊多属晚期,手术切除率低,仅为10%~20%,术后5年生存率也只有1%~5%.但如果能早期发现胰腺癌,早期手术治疗则可以显著改善病人预后[1].近年来随着内镜学的发展,通过内镜技术(ERCP或EUS)获取胰液、胰腺细胞学及组织学标本进行相关的肿瘤标志物及基因检测,可明显提高胰腺癌的早期诊断率.本文就该领域的研究及临床应用状况介绍如下。
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