Abstract
Pancreatic lesions are very common and the pancreatic cancer is one of the most fatal cancers. The aim of the study was to show the value of diffusion weighted MRI in evaluation of pancreatic lesions, especially pancreatic cancer and to correlate the results of DW MRI with that of pathology or tumor markers aiming to use DWI MRI as a reasonable alternative modality especially when contrast administration is contraindicated. The study included 30 patients performed in the radiology department, El-Hussein Hospital University as well as a private center. The age of the patients ranged from 27 to 76 years (mean =51.13). MR imaging was performed on high field system (1.5 Tesla) magnet units (Philips Acheiva) and siemens. The ADC value of malignant pancreatic tumors was significantly lower than that of the normal pancreas with mean values of 1.27±0.21×10-3 mm2/sec and 1.61±0.13×10-3 mm2/sec respectively. Sensitivity of DW MRI was 95.5%, specificity 75%, NPV 85.7 % and PPV 91.3%, while Sensitivity of contrast enhanced MRI was 95.5 %,specificity 62.5 %,NPV 83.3 % and PPV (positive predictive value) 87.5%.
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