Value of computed tomography venography in the evaluation of post-thrombolic syndrome and nonthrombotic iliac vein lesions

Abstract

Objective To investigate the value of computed tomography venography (CTV) in the evaluation of post-thrombolic syndrome (PTS) and nonthrombotic iliac vein lesions (NIVL). Methods Clinical data of patients with PTS or NIVL experienced both CTV and digital subtraction angiography (DSA) examination in our department from January 2014 to February 2016 were analyzed retrospectively. The differences of two methods in the diagnosis of PTS and NIVL were compared. Results One hunderd and fifty-eight consecutive patients, 96 for PTS and 32 for NIVL, were presented. Compared with DSA in diagnosis of PTS and NIVL, CTV's sensitivity, specificity, Youden index, positive likelihood ratio and negative likelihood ratio was 94.8% and 93.8%, 87.1% and 96.0%, 0.819 and 0.898, 7.35 and 23.45, 0.06 and 0.06, respectively. Both Kappa values were> 0.7 and there was no significant difference (P>0.05, McNemar test) between the two groups. Both area under curves (AUC) were > 0.9 showed by receiver operating characteristic (ROC) curve. Conclusions CTV is remarkable in sensitivity and specificity for PTS and NIVL, which is consistent with DSA. There are no significant differences between CTV and DSA in the diagnosis of PTS and NIVL. CTV is important for the diagnosis and preoperative assessment of PTS and NIVL. Key words: Post-thrombolic syndrome; Nonthrombotic iliac vein lesions; Computed tomography venography; Digital subtraction angiography